Bio-structures
and Biomaterials (Biostructuri si Biomateriale)
Head: Nicanor I. MOLDOVAN, PhD, Ohio State University, Columbus, OH, USA
Members:
Mihai
Oana Claudia, BA, University of Bucharest, Romania
Alin
Velea, PhD, IFIN-HH Bucharest, Romania
Nicoleta
Roman, PhD, Ohio State University, Lima Campus, OH, USA
Anca
I. Stefan, PhD, Lawrence Technical University, Detroit, MI, USA
Jason
Carrier, PhD, Ohio State University, Columbus, OH, USA
Research
Directions:
1.
Hydrophobic interaction as driving force for self-organization of bio-nanostructures
and higher-scale cellular components.
2.
Live cells as tools for purposeful processing of biomaterials.
Publications:
Direction
1:
Mihai
C., Velea A., Roman N., Tugulea L., Moldovan N. I. Impact of solute molecular properties
on the organization of nearby water: A cellular automata model. D. J. Nanomater.
Biostruct. 2012, 7: 469 – 475
Lenormand
G., Millet E., Hardin C., Butler J. P., Moldovan N. I. Fredberg J. Dynamics of the
cytoskeleton: How much does water matter? 2011, Physical Review Letters, E , 83:061918.
Direction
2:
N.
I. Moldovan, P. Goldschmidt-Clermont, J. Parker-Thornburg , P. E. Kolattukudy, Contribution
of Monocytes/Macrophages to Compensatory Neo-Vascularization: Drilling of Metalloelastase-Positive
Channels. Circ. Res. 87:378-384, 2000 (Editorial: Mining the Myocardium With Macrophage
Drills : A Novel Mechanism for Revascularization, by M. P. Bendeck, Circ. Res. 87:341–343,
2000).
N.
I. Moldovan, S. Kulkarni , M. Ferrari. Use of Laser Scanning Cytometry for Analysis
of Endothelial Cells Attached to Micropatterned Silicon Surfaces. Sensors and Materials
14:179-187, 2002.
S.
Kulkarni, R. Orth, M. Ferrari, N. I. Moldovan. Micropatterning of endothelial cells
by guided stimulation with angiogenic factors. Biosensors and Bioelectronics, 2004,
19: 1401-7.
K.
E. Orosz, S. Gupta, M. Hassink, M. Abdel-Rahman, L. Moldovan, F. Davidorf, N. I.
Moldovan. Delivery of Antiangiogenic and Antioxidant Drugs of Ophthalmic Interest
Through a Nanoporous Inorganic Filter. Mol. Vis., 2004, 10: 555-565.
Anghelina
M., Krishnan, P., Moldovan, L., Moldovan, N.I. Monocytes/Macrophages Form Branched
Cell Columns in Matrigel in Vitro and in Vivo: Implications for Their Role in Neovascularization,
Stem Cells Dev. 2004, 13: 665-676.
Anghelina,
M., Krishnan P. Moldovan, L. Moldovan, N. I. Monocytes/Macrophages cooperate with
progenitor cells during neovascularization and tissue repair: Conversion of cell
columns into fibro-vascular bundles Am. J. Pathol., 2006, 168:529-541.
Butt
OI; Kutala VK, Kuppusamy P, Moldovan N. I. Tissue engineering of peri-implant neovascularization
with bone marrow-derived progenitor cells: Monitoring by in vivo EPR oximetry. Tissue
Eng.. 2007, 13:2053-61. (Special Issue on ‘Emerging Technologies and New Basic Science
Directions in Tissue Engineering’).
Smith
BR, Heverhagen J, Knopp M, Schmalbrock P, Shapiro, J Shiomi M, Moldovan, N. I.,
Ferrari M, Lee SC. Localization to atherosclerotic plaque and biodistribution of
biochemically derivatized superparamagnetic iron oxide nanoparticles (SPIONs) contrast
particles for magnetic resonance imaging (MRI). Biomedical Microdevices, 2007, 9:719-27.